Medical reviewer
Holds the Cushing Professorship of Medicine at Yale School of Medicine. Served as the founding director of the Yale Obesity Research Center. Acted as lead investigator on the pivotal trials of retatrutide, tirzepatide and maridebart cafraglutide.
Education and training
| Stage | Institution | Year |
|---|---|---|
| BA in Art History with a minor in music, magna cum laude | Bucknell University | 1998 |
| MD | University of Maryland at Baltimore | 2002 |
| Residency training in Internal Medicine / Pediatrics | University of Maryland School of Medicine | 2006 |
| Completed dual fellowships in Adult and Pediatric Endocrinology | Yale School of Medicine | 2011 |
| PhD, Investigative Medicine | Yale Graduate School | 2012 |
Board certifications
Holds board certification across five specialties: internal medicine, pediatrics, endocrinology/diabetes/metabolism, pediatric endocrinology, and obesity medicine.
Current positions
- Harvey and Kate Cushing Professor of Medicine (Endocrinology), Yale School of Medicine
- Professor of Pediatrics (Endocrinology)
- Founding Director, Yale Obesity Research Center (Y-Weight)
- Co-Director, Yale Center for Weight Management
Research areas
Obesity pharmacotherapy; nutrient-stimulated hormone (NuSH)-based therapies; the neurobiology of obesity explored through fMRI and PET neuroimaging; how anti-obesity medications work; large multicentre clinical outcomes trials.
112 publications, 12,422 citations.
Lead investigator on landmark trials
All published in the New England Journal of Medicine:
- Tirzepatide (dual GIP/GLP-1 receptor agonist), SURMOUNT programme, NEJM 2022 and 2024
- Retatrutide (triple GIP/GLP-1/glucagon receptor agonist), NEJM 2023
- Maridebart cafraglutide / MariTide (GIP receptor antagonist / GLP-1 receptor agonist), NEJM 2025
Book
Enough: Your Health, Your Weight, and What It's Like To Be Free co-authored with Oprah Winfrey. Simon & Schuster, January 2026. #1 National Bestseller.
Awards
The Obesity Society Clinician of the Year (2023), NIH/NIDDK K23 Mentored Patient-Oriented Research Career Development Award (2014), New York Times Best-Selling Author (2026).
Profiles and links
Research-grade · COA per lot